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br Testing these pathways has particular relevance in
2021-03-04
Testing these pathways has particular relevance in the context of cancer. In a sample of breast cancer patients, reductions in the CTRA following CBSM were associated with longer disease-free survival over 8–15 years of follow-up (Antoni et al., 2016). Lower CTRA gene ex-pression profiles were als
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br Characteristics of NLCs br Biotin SUN NLCs
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3.2. Characteristics of NLCs Biotin-SUN-NLCs were prepared using the emulsion-solvent Fig. 1. 1H NMR spectra of (A) Biotin (B), stearylamine and (C) Biotin-stearylamine conjugate. diffusion and Y-27632 method. Irregular factorial design was em-ployed to evaluate the effect of several for
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br miR b and miR Increase
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miR-99b and miR-485 Increase the Expression of Viral Genes To further characterize AdwtE miR-99b and AdwtE miR-485, we analyzed the mRNA levels of late (hexon and fiber) and immediate early (E1A) genes at 24 or 8 hr PI, respectively, in PANC-1 and MIA PaCa-2 cells. Increased mRNA levels of the
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br Time lapse recording of
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2.6. Time lapse recording of the spheroid forming process Cells were stained with the fluorescence kits as mentioned. The formation of spheroids was tracked by a time-lapse recording system (Real Time Cell Culture Monitoring (CCM) System, Astec) operated in the fluorescence mode. Cells were ima
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br around the CD stained neo vasculatures Compared
2020-08-28
around the CD31-stained neo-vasculatures. Compared with control, the deficiency in catecholamines caused a significant reduction in MVD and M2 density in lung cancer models. After 6OHDA treatment, the MVD dropped to less than half of those in control groups in both the H446 and HCC827 models wi
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br Results br Qualitative assessment br The aerial parts
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3. Results 3.1. Qualitative assessment The aerial parts of the four C. curetum solvent fractions contained a wide range of secondary metabolites, as shown in Table 1. The results show that the aqueous fraction was rich in secondary and primary metabolites including flavonoids, tannins, pheno
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Cancer Letters br Cells and culture conditions br Human
2020-08-28
Cancer Letters 444 (2019) 70–81 2.3. Cells and culture conditions Human pancreatic stellate cell (PSC) lines were established from fresh surgical specimens of pancreatic cancer using the outgrowth method [21–23]. Pancreatic cancer cell (PCC) lines from the primary tumors of KPC mice were al
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br Time months br survival br Overall br Patients at
2020-08-28
Time (months) survival Overall Patients at Risk Time (months) C free survival 0.75 -Progression Patients at Risk Time (months) survival Overall Patients at Risk Time (months) Abbreviations: ALDH ¼ aldehyde dehydrogenase; EGFR ¼ epidermal growth factor rec
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br to examine angiogenesis in brain
2020-08-28
to examine angiogenesis in beta-Nicotinamide mononucleotide tumours. As shown in Fig. 5J-K, tu-mours treated with BCF showed significant decrease in micro-vessel density, demonstrating that BCF decreases miR-1246 levels in exosomes to inhibit angiogenesis in brain microenvironment. In addition to
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ref br cMET cellular Mesenchymal Epithelial Transition facto
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ref. cMET: cellular Mesenchymal Epithelial Transition factor, ALK: Anaplastic Lymphoma Kinase, LCLC: Large-Cell Lung Cancer, NOS: Not Otherwise Specified, HR: Hazard Ratio, Ref: Reference, CI: Confidence Interval. 4. Discussion The role of c-MET protein overexpression as a prognostic and
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br BCRP overexpression attenuates HY accumulation in
2020-08-24
3.2. BCRP overexpression attenuates HY accumulation in cBCRP cells To define the extent of the impact of particular ABC transporter overexpression on intracellular HY content, we measured the kinetics of HY incorporation into the Butyrolactone I by flow cytometry. Analyses of HY content were p
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systems br Khosravia et al Deep convolutional
2020-08-18
systems Khosravia et al. [11] 2018 Deep convolutional neural Classifying the various Increase the precision of Computation cost was not networks (CNN) cancer tissues diagnosis and minimizes minimized the error Sharma et al. [18] 2018 Two-stage hybrid ensemble Classifying the c
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br Holmqvist AS Olsen JH
2020-08-18
[10] Holmqvist AS, Olsen JH, Andersen KK, de Fine Licht S, Hjorth L, Garwicz S, et al. Adult life after childhood cancer in Scandinavia: T16AinhA01 following treatment for cancer in childhood. Eur J Canc 2014;50(6):1169e75. [11] Wilson CC, Liu W, Yang JJ, Kang G, Ojha RP, Neale GA, et al. Gene
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br Schulman S Kearon C Definition of major
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15. Schulman S, Kearon C. Definition of major bleeding in clinical investi-gations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost 2005;3:692–694. 17. Sherwood MW, Douketis JD, Patel MR, Piccini JP, Hellkamp AS, Lokhnygina Y, Spyropoulos AC, Hankey GJ, Singer DE,
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br In the present study di erent ratios of PSCs
2020-08-18
In the present study, different ratios of PSCs could mimic the dif-ferent stages of PDAC spheroids. Some literature has shown that the prominent stromal reaction of increased alpha-smooth muscle NS638 (α-SMA) expression can lead to the worse outcomes on pancreatic cancer patients [48,49]. The lite